Genetic Research Analyst Resume
SUMMARY
- Aspiring for growth - oriented opportunities in Biotechnology and Life sciences involving Research & Development with an organization of repute, as well as to achieve excellence through positive attitude & to utilize my knowledge & skills in Biology to the fullest extent.
- Presently working as “Genetic Research Analyst” in Confidential, Ossining, New York.
- Worked as “Senior Genetic Research Analyst” and “Team Leader (Biotech. domain)” in Confidential.
- Four years experience in Human Leukocyte Antigen (HLA) gene sequencing by Sequence Based Typing (SBT) as well as in various Clinical, Leukemia patient- donor HLA code matching of hospitals like Apollo-New Delhi, Apollo-Chennai, CMC Vellore, Confidential and World Donor Registries like NMDP & DKMS for related or unrelated Bone Marrow Donor Transplantation. Presently in learning phase of Next Generation Sequencing (NGS).
- Experience in Interviewing & Training new employees, coordinating onshore & offshore team of 40 members.
- Two years experience as Practice School Co-ordinator.
- Selected as “CSIR Research Intern” in Institute of Microbial Technology, Chandigarh and Worked as Biochemist in Confidential.
- Keen interest in subjects like Biotechnology & Pharmaceutical Research and Market research, Biochemistry, chemistry, Pharmaceutical chemistry, Toxicology, Immunology, Molecular Biology, Genetic Engineering, Microbiology, Environmental Biotech, Fermentation Technology, Bioinformatics or any area related to Biotechnology & Life Sciences.
- In depth understanding of techniques like PCR, Real Time PCR, ELISA, Cloning and Transformation, Spectrophotometry, SDS PAGE, Pharmaceutical drugs production and their quality control and microbial checking, Fermentation, Plant and Animal cell culture, HPLC, GLC, Ion exchange chromatography, Micro-filtration, Enzyme immobilization, Single Nucleotide Polymorphism.
- Skilled with ability to analyze and interpret unique problems, with a combination of training experience and logical thinking to get the right solutions.
- Three months course in Intellectual Property Rights from Indian Law Institute, New Delhi.
- Actively Participated in Academic meet APOGEE-2008 held at BITS, PILANI.
- Computer Skills: Word processing, spreadsheets, databases, web publishing and HTML.
- Leadership: Exceptional communication, organizational, public speaking and mentoring skills
PROFESSIONAL EXPERIENCE
Confidential
Genetic Research AnalystResponsibilities:
Biochemical studies (Proteoglycan, Collagen and total protein) on Chondrocyte cell culture done to study Osteoarthritis by in-vitro suspension culture in alginate gel matrix using Articular Cartilage tissue of goat knees as source. For Proteoglycan analysis Alcian Blue Dye Binding, for Collagen Eldrich method and for Total Protein Lowry method done. Chondrocyte cell’s protease activity studied by Casein Hydrolysis method. Effect of metal ions (Mn, Cu, Mg) on proteases and EDTA inhibitory effect on these metalloproteases were also studied.
Confidential
Genetic Research AnalystResponsibilities:
Proteomic studies (SDS-PAGE & Isoelectric focusing method) done to differentiate GM & Non-GM maize. DNA from maize seeds, popcorn, cornflakes, various maize food products & GM maize MON810 (0%, 1%,1.5%,2%,2.5% & 5%) isolated. PCR & Real- Time PCR done to detect GM content in maize food products using primers for housekeeping gene “Starch Synthase” 35S Promoter & transgene Cry1A (b) as only upto 1% GM content in food products is allowed for human consumption because it causes allergy.
Confidential
Genetic Research AnalystResponsibilities:
Project was related to case studies of Acute & Chronic Pancreatic Cancer. Plasma and Serum samples of patients were used to detect these cancers using Cathepsin-L as a marker by Sandwich ELISA method. It had been found that plasma sample gives more better detection result in comparison of serum as it has inhibitory proteins.
Confidential
Genetic Research AnalystResponsibilities:
Specialized high-resolution molecular typing i.e. Sequence Based Typing (SBT) is performed on HLA (Human Leukocyte Antigen) genes A, B, C, DR & DQ present on the donor's and recipient's cells of unrelated hematopoietic stem cell (HSC) transplantation and helps in decrease in transplant related mortality due to graft vs. host disease (GVHD). In India, the number of transplants performed till now is around 500. In result, among six Asians, High Resolution HLA match 4 of 6 (N=5) & 5 of 6 (N=1) has been found and best HLA match is influenced by recipient ethnicity. Thus, in Asians 1 of 6 (70%) & 2 of 6 (30%) potential HLA mismatch is most common.