We provide IT Staff Augmentation Services!

Pharmaceutical Chemist Resume

SUMMARY:

Ambitious, conscientious professional with comprehensive laboratory and manufacturing experience at large and small, family - style organizations. Eager to learn new techniques, continuing my career in pharmaceuticals. Excellent project management skills, coordinating scientific studies independently and in collaboration with multi-disciplinary project teams, driving adherence to budgets and timelines. Adept in regulated environments. Articulate and engaging. Experience working with controlled substances.

EXPERTISE AREA:

  • Skilled researcher
  • Dedicated/agile
  • Problem solver
  • R&D/analytical
  • Product/method development
  • Observant/investigative
  • Practical ingenuity
  • Integrity/GLP/cGMP
  • Leader/collaborator
  • Innovative, quality-focused, and goal-oriented, demonstrating perseverance to achieve desired outcomes for customers.

LABORATORY SKILLS:

  • Polymorph screening (solid form screening), including stable form screening and hydrate/solvate determinations
  • Challenging crystallization, including single crystal growth for structure determination
  • Salt/cocrystal screening
  • Amorphous material generation
  • Solubility determination
  • Wet chemistry techniques, organic and inorganic, including titration, extraction, and pH adjustment
  • Rotary evaporation, distillation, lyophilization, and loss on drying
  • Formulation preparation and testing, including amorphous dispersions
  • Experience with small and large molecules, including controlled substances, teratogens, cytotoxics, and moisture or light-sensitive materials

INSTRUMENTATION SKILLS:

  • Atomic absorption | Optical microscopy, including hot stage | GC/MS | IR | Raman
  • Thermal analysis, including DSC and TGA | XRPD | Micro VanKel dissolution
  • USP VanKel dissolution, including initial instrument setup and automated testing using UV flow cell; paddle, basket, or intrinsic, including pellet pressing (Woods apparatus);
  • UV-VIS (spectrophotometer), pH meter.

SOFTWARE SKILLS:

Microsoft Office (Word, Excel, PowerPoint, Outlook) | Omnic | Grams | ACD Labs | ChemDraw PatternMatch (proprietary) | Mercury | PowderCell | UN-SCAN IT | StarLIMS |MiniTab

PROFESSIONAL EXPERIENCE:

Confidential

Pharmaceutical Chemist

Responsibilities:

  • Collected and interpreted analytical data for drug substance and drug product, readily making connections between the data about the nature of the materials tested.
  • Conducted independent research on novel cocrystals and ‘crystalline sponges’, for structure determination of hard-to-crystallize materials, including liquids
  • Discovered numerous new materials, resulting in enhanced stability or solubility of drug substance and IP protection for clients.
  • Planned and executed scale-up for generation of several materials, allowing for more complete characterization and providing crystalline seeds for clients to produce newly discovered materials.
  • Prepared crystals leading to structure determination which verified new crystalline phases.
  • Determined API chirality for enantiomers or diastereomers prepared from complex synthetic pathways.
  • Increased understanding of material properties, particularly solvent interactions.
  • Engaged in various forums for discussion of specific projects and methods as well as CMC and regulatory requirements.
  • Active collaboration with inter-departmental and cross-functional groups, completing multifaceted projects efficiently.
  • Advised and trained colleagues on specific techniques, increasing their efficiency in project completion.
  • Regular thorough, consistent review of colleagues’ documentation for cGMP compliance.
  • Created reports for clients to provide material understanding and sections for patents and FDA filings.
  • Dedicated to finding solutions for clients, focusing on identifying best solids for advancement and providing insight into process conditions, thereby reducing costly manufacturing issues.
  • Frequent customer interaction, leading conference calls.
  • Persuaded clients to expand/change project scope and/or to change process or target solid form of API, when appropriate, based upon my scientific judgement and team consensus.

Confidential

Pharmaceutical Chemist

Responsibilities:

  • Developed quantitative analysis method for percent crystallinity of drug substance through XRPD.
  • Planned and performed stability studies on drug powders in to their change in crystallinity or polymorphic form, as measured by DSC and XRPD.
  • Aided in salt and form selection for drug candidates.
  • Prepared and tested parenteral drug product formulations.

Confidential

Associate Engineer

Responsibilities:

  • Engaged in troubleshooting of manufacturing problems for prototypes as well as mass-produced current products.
  • Maintained various records, including repeatability studies, calibration records, and Safety Data Sheets.
  • Led discussions for the safety program.

Confidential

Laboratory Chemist

Responsibilities:

  • Statistical tracking of measurements for repeatability and accuracy.
  • Prioritized testing of samples according to hold time and testing efficiency.

Hire Now