SUMMARY:

• Computational scientist with extensive business management experience.
• Over 30 years of experience, from start - up companies to Fortune 50. Entrepreneur; co-founder and/or seed-stage employee in five high-tech start-ups, three of which were highly profitable; one IPO.
• Skilled in algorithm development, team leadership, management and planning.

SKILL:

Architecture: TOGAF; SDLC, Sparx Systems Enterprise Architect, UML; Service Oriented Architecture (SOA), web services; cloud MS Azure, BT Cloud Compute, Amazon AWS; Load Balancing (Citrix, F5).

Business Systems: MS Sharepoint; multiple CMS and Wiki systems; Salesforce.com, Sugar CRM; Ariba, ERP (J. D. Edwards, SAP), Learning Management Systems (LMS ISOtrain, Blackboard, Sum Total), QMS/Change Management (Sparta Systems Trackwise); MS Project and MS Project Server; versioning Redmine, Jira, Subversion (SVN), CVS; helpdesk management (Peregrine).

Quality and compliance management: knowledge of formal systems validation procedures, IQ, OQ, PQ, test-driven development, unit and regression testing; prior experience with external vendor audits and internal IT compliance audits; Design History File (DHF) development and maintenance, 21CFR11 requirements; SOX; ISO 9001, 13485; GxP, GAMP, HIPAA.

Data warehousing, database development, reporting and business intelligence: Oracle, SQL, PL/SQL, Erwin; MySQL; Mongo DB; Hadoop, HBase.

Programming: UNIX (Linux (Red Hat, Ubuntu, SuSe), Solaris, SGI IRIX); all versions of Windows from 3.1 to 10; C/C++, Ruby, PHP, Fortran; Java, J2EE; R (GNU S+), MATLAB; XML; High-Performance Computing and parallel programming (MPI, LSF).

PROFESSIONAL EXPERIENCE:

Confidential, La Jolla, CA

Sr. IT Product Manager

Responsibilities:

• In charge of commercial and technical development of BaseSpace Sequence Hub, Confidential software platform.
• Prioritized requirements, wrote technical marketing literature, consulted on Scrum project management, release process improvements, team and business unit alignment, and the Confidential Clinical Transformation program.

Confidential, El Segundo, CA

Life Sciences Project CTO

Responsibilities:

• Pioneered projects in regulatory compliance and computer systems validation in the cloud, Big Data mining, translational research PaaS, cloud collaborative research management service, digital transformation of supply chain and distribution.
• Managed collaborations with the Genomics Institute of Singapore.
• Managed technical requirements for BT Cloud Compute offerings, developed contracts and statements of work, introduced BT to decision makers in prospective client companies, consulted on risk-based project management, ran industry-specific computing benchmarks, trained sales staff.

Confidential, Thousand Oaks, CA

Co-Founder

Responsibilities:

• Confidential commercialized computational ancestry algorithms developed at the University of Southern California .
• Complete cycle of corporate development from initial license agreement negotiation to product marketing in a highly profitable business.

Confidential, Thousand Oaks, CA

Founder and Principal

Responsibilities:

• Research in the statistical methods for biomarker discovery from multidimensional - omics data and systems biology.
• Important technology applications include discovery and validation of gene expression biomarker panels for exposure detection to multiple chemical threats, radiation poisoning, and diagnostic panels for certain cancers, in particular, Oral Squamous Cell Carcinoma (OSCC). Manuscript in preparation.
• Complete profit and loss responsibility.
• Hired and trained the development team, selected technologies and tools, set objectives, managed budgets, analyzed risks, conducted development iterations, interacted with the DoD and other federal agencies, prepared periodic project reports to the US Army standards.

Confidential, Cambridge, MA

Bioinformatics and Data Management Lead (Director)

Responsibilities:

• Turned around the performance of the data management group by applying the best practices in business-IT alignment, project portfolio prioritization, and agile project management.
• Managed budgets, projects, and a team with multiple FTEs, contractors, and matrixed relationships.
• Developed IT processes and process improvement plans.
• Participated in long-term information management strategy planning for the Protein Optimization Program and later for the Enabling Technologies organization.
• Managed integration of the Cambridge site systems with the company-wide LIMS (Labware).

Confidential, Westlake Village, CA

Consultant, Scientific IT Project Manager

Responsibilities:

• Architected enterprise solutions for automated data capture from analytical instruments, ELN, LIMS and long-term information retention.
• Developed risk-based validation plans for these systems.
• Provided IT Management expertise.
• Advised client on stakeholder, expectation and risk management and iterative project development approaches.
• Wrote contracts for engagements with multiple third-party vendors, managed parts of Confidential ’s relationship with IBM, planned vendor audits.

Confidential, La Jolla, CA

Consultant, Global Project Manager

Responsibilities:

• In charge of development of Outsourcing Relationship Management (ORM) system that serves as an Electronic Data Interchange (EDI) between Confidential and its worldwide medicinal chemistry and screening research partners.
• Introduced iterative project management methodology
• Re-negotiated contracts with vendors and consultants in favor of Confidential by tying payments to specific deliverables and time lines.
• Managed project schedule and budget. Mentored and coached associates.
• Delivered on time and under budget.

Confidential, Thousand Oaks, CA

Sr. Business Analyst

Responsibilities:

• Created information systems development strategy for the global Process Development and Clinical Operations.
• Developed business cases for projects to implement the designed strategy, with estimated NPVs ranging from $2 million to $50 million.
• Pioneered a number of management methodologies at Confidential: Whitaker 4 column strategy analysis, RUP project management, techniques for financial valuation of IT investments and quantitative models for work order queues, earning high praise from executive management.

Confidential, Thousand Oaks, CA

Manager of Research Computing

Responsibilities:

• Tripled the yield of finished sequence through improvements to quality control procedures.
• Supervised a diverse team of bioinformatics and IT professionals.