Architect Resume
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SUMMARY:
- Bioinformatics scientist and architect with background in molecular biology.
- Passionate about solving new, tough problems in life sciences and beyond.
- +5 years’ experience with all stages of Next Generation Sequencing, including data analysis, data QC/QA, experimental design, and sample preparation
- Developed tools and pipelines for processing and analyzing large RNAseq data sets
- Developed methods and pipelines for detecting novel gene isoforms and test for differential expression
- Contributed to annotation of the first sequenced amphibian genome ( Confidential ) and assigned human gene symbols to all genes in v7.2 using an iterative Confidential method. This improved method increased from 50% to +90% the total of named genes
- Assigned Gene Ontology terms based on sequence homology to the frog proteome to determine coherent gene set regulation
- Background in embryo development, cell differentiation, gene expression, and metabolism
- Mentored lab members in experimental design and data analysis
- First - author publications and co-authorships in top journals
SKILL:
- Data mining, analysis, visualization, and reporting
- Excellent understanding of statistics and experimental design
- R / Bioconductor; Python: NumPy / Pandas / scikit - learn (basic)
- Tophat, Cufflinks, SAMtools, BEDtools
- Analysis of gene expression data using Next Generation Sequencing
- Functional genome annotation and integration with public databases
- Supervised and unsupervised data modeling (basic)
- R (+5 years’ experience), Python (1 year), Perl (4 years), and shell (+5 years)
- Database querying and basic management (MySQL and Oracle); basic NoSQL
- Cluster computing and batch job management in a distributed Linux environment
- Expert molecular biologist with +10 years’ experience (DNA / RNA / antibodies / histology)
- Generation and phenotypic analysis of mutant and transgenic animals
- Ambitious, pragmatic, and self-motivated team player
- Detail oriented with excellent organizational and communication skills
WORK EXPERIENCE:
Confidential
Architect
Responsibilities:
- Working with Confidential clients to implement and test Life Science enterprise solutions
Confidential
Bioinformatics Consultant
Responsibilities:
- Gene expression analysis using Next Generation Sequencing
Confidential
Associate Specialist, Staff
Responsibilities:
- Analysis of mouse and frog gene expression data
- Bioinformatics and functional analysis of mRNA splicing
- Annotation of frog genomes
Confidential
Post-Doctoral Research Fellow
Responsibilities:
- High-throughput screening for novel gene functions and transcriptional regulation
Confidential
Research Scientist
Responsibilities:
- Characterized endocrine pancreas development in FGF and TGF-beta mutant mice