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Architect Resume

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SUMMARY:

  • Bioinformatics scientist and architect with background in molecular biology.
  • Passionate about solving new, tough problems in life sciences and beyond.
  • +5 years’ experience with all stages of Next Generation Sequencing, including data analysis, data QC/QA, experimental design, and sample preparation
  • Developed tools and pipelines for processing and analyzing large RNAseq data sets
  • Developed methods and pipelines for detecting novel gene isoforms and test for differential expression
  • Contributed to annotation of the first sequenced amphibian genome ( Confidential ) and assigned human gene symbols to all genes in v7.2 using an iterative Confidential method. This improved method increased from 50% to +90% the total of named genes
  • Assigned Gene Ontology terms based on sequence homology to the frog proteome to determine coherent gene set regulation
  • Background in embryo development, cell differentiation, gene expression, and metabolism
  • Mentored lab members in experimental design and data analysis
  • First - author publications and co-authorships in top journals

SKILL:

  • Data mining, analysis, visualization, and reporting
  • Excellent understanding of statistics and experimental design
  • R / Bioconductor; Python: NumPy / Pandas / scikit - learn (basic)
  • Tophat, Cufflinks, SAMtools, BEDtools
  • Analysis of gene expression data using Next Generation Sequencing
  • Functional genome annotation and integration with public databases
  • Supervised and unsupervised data modeling (basic)
  • R (+5 years’ experience), Python (1 year), Perl (4 years), and shell (+5 years)
  • Database querying and basic management (MySQL and Oracle); basic NoSQL
  • Cluster computing and batch job management in a distributed Linux environment
  • Expert molecular biologist with +10 years’ experience (DNA / RNA / antibodies / histology)
  • Generation and phenotypic analysis of mutant and transgenic animals
  • Ambitious, pragmatic, and self-motivated team player
  • Detail oriented with excellent organizational and communication skills

WORK EXPERIENCE:

Confidential

Architect

Responsibilities:

  • Working with Confidential clients to implement and test Life Science enterprise solutions

Confidential

Bioinformatics Consultant

Responsibilities:

  • Gene expression analysis using Next Generation Sequencing

Confidential

Associate Specialist, Staff

Responsibilities:

  • Analysis of mouse and frog gene expression data
  • Bioinformatics and functional analysis of mRNA splicing
  • Annotation of frog genomes

Confidential

Post-Doctoral Research Fellow

Responsibilities:

  • High-throughput screening for novel gene functions and transcriptional regulation

Confidential

Research Scientist

Responsibilities:

  • Characterized endocrine pancreas development in FGF and TGF-beta mutant mice

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